We keep our blue planet in mind with every choice that we make and we honor our need for balance within our lives and in those of the people with whom we work. We value sustainability in all forms - for our planet, for each other, and for ourselves. We recognize that joy often comes from the playfully unexpected and we strive to maintain a culture of merriment while creating charming wonder for our clients and guests. We hold our work to the highest standards of excellence, paying close attention to deliver superior quality, and striving for a unique level of professionalism that captures and delivers upon every minute detail. We exhibit compassion, kindness, and integrity for everyone with whom our paths cross. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.We serve our clients at the highest level and we recognize that hospitality must extend to everyone we interact with, including vendors, colleagues, and competitors. Dr. Maehara is a consultant to and has received research and grant support from Boston Scientific Corporation and has received lecture fees from St. Dr. Virmani is a consultant for and/or has received honoraria and/or research support from Abbott Vascular, Atrium, Biosensors International, Boston Scientific Corporation, CeloNova, Cordis Corporation, GlaxoSmithKline, Kona Medical, Lutonix, Medtronic, Microport Medical, Orbus Neich, ReCor Medical, SINO Medical Technology, Terumo Corporation, Merck, 480 Biomedical, and W.L. Muller has equity ownership in InfraReDx. Stone is a consultant to Boston Scientific Corporation, Volcano Corporation, and InfraReDx. Goldstein is a consultant to and an equity owner in InfraReDx. Burke and Virmani were consultants to InfraReDx for histological studies. Drs. Sum, Madden, and Muller are current employees of InfraReDx. Mr. Biro is a current employee of Volcano Corporation. Mintz has received consulting fees from Boston Scientific Corporation, InfraReDx, and Volcano Corporation and has received research grant support from Volcano Corporation. Pu has received research grants from the National Natural Science Foundation of China ( 81170192/81270282) and Boston Scientific. Comparisons between IVUS and near-infrared spectroscopy revealed that echo-attenuated plaques contained the highest probability of near-infrared spectroscopy–derived lipid core plaque, followed by echolucent plaques and spotty calcifications.ĭr. IVUS spotty calcification, especially when superficial in location (72.6%), was often associated with an FA with calcium deposits and had smaller arcs of calcium in the setting of FA compared with fibrocalcific plaques (37.5° vs. 90° ), although 82.8% of superficial echolucent zones indicated an NC-containing FA. Echolucent plaques indicated the presence of a relatively smaller lipid or NC compared with echo-attenuated plaques (thickness: 0.51 mm vs. Histopathologically, 91.4% of echo-attenuated plaques corresponded to either a fibroatheroma (FA) with a necrotic core (NC) or pathological intimal thickening with a lipid pool almost all segments with superficial echo attenuation indicated the presence of an FA with an advanced NC. IVUS detected echo-attenuated plaques in 18.3% of segments, echolucent plaques in 10.5% of segments, and spotty calcification in 14.4% of segments.
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